Drug Information

Clozapine 25 mg (CLORIL) 

 

 


  Indications

1.Treatment of schizophrenia.

2.Treat other diseases or conditions as directed by the physician.   Click to listen highlighted text! Indications 1.Treatment of schizophrenia. 2.Treat other diseases or conditions as directed by the physician.


  Contraindications and precautions

1.Do not use if you had an allergic reaction to this medication or its components.

2.Do not use in patients with neutropenia.

3.Use this medication cautiously in lactating women as safety data are not established.

4.Use this medication cautiously in patients with epilepsy.

5.A dose adjustment may be necessary in patients with hepatic impairment or renal impairment or taking certain medications.

If you have any of these conditions, you should inform your physician.

6.Concomitant use with other drugs may result in drug-drug interactions. There are many drugs that may interact with this medication. You should take counsel with physicians or pharmacists.   Click to listen highlighted text! Contraindications and precautions 1.Do not use if you had an allergic reaction to this medication or its components. 2.Do not use in patients with neutropenia. 3.Use this medication cautiously in lactating women as safety data are not established. 4.Use this medication cautiously in patients with epilepsy. 5.A dose adjustment may be necessary in patients with hepatic impairment or renal impairment or taking certain medications. If you have any of these conditions, you should inform your physician. 6.Concomitant use with other drugs may result in drug-drug interactions. There are many drugs that may interact with this medication. You should take counsel with physicians or pharmacists.


  Recommendations of drug use

1.This medication must be taken continuously for at least 2 weeks so the medication starts effects, and it may take longer to see full results.

Take the dosage as directed by your physician. Do not increase the dosage or stop taking the medication on your own.

2.If you miss the dose, take the dose as soon as possible after realizing you missed it. If you're getting close to the next dose, skip the dose and take the next dose at its regular time. Don't double the dose.

3.The effects during initial treatment are often side effects of the medication.

Side effects such as drowsiness, fatigue, increased appetite, or loss of appetite are common. They're usually mild and gradually go away.

4.Avoid or abstain from alcohol consumption during treatment.

5.You need to be careful if you drive or operate machinery or work at height.

6.Monitoring white blood cell count is required in patients taking this medication.   Click to listen highlighted text! Recommendations of drug use 1.This medication must be taken continuously for at least 2 weeks so the medication starts effects, and it may take longer to see full results. Take the dosage as directed by your physician. Do not increase the dosage or stop taking the medication on your own. 2.If you miss the dose, take the dose as soon as possible after realizing you missed it. If youre getting close to the next dose, skip the dose and take the next dose at its regular time. Dont double the dose. 3.The effects during initial treatment are often side effects of the medication. Side effects such as drowsiness, fatigue, increased appetite, or loss of appetite are common. Theyre usually mild and gradually go away. 4.Avoid or abstain from alcohol consumption during treatment. 5.You need to be careful if you drive or operate machinery or work at height. 6.Monitoring white blood cell count is required in patients taking this medication.


  Adverse Reactions

1.This medication may cause drowsiness, insomnia, increased weight, headache, blurred vision, dry mouth and throat, abnormal menstruation, breast engorgement and galactorrhea, syncope, orthostatic hypotension.

2.This medication may cause obesity. Risk of epilepsy is increased.

3.If you take this medication and many of these symptoms occur together such as: fever, muscle spasm, myoclonus, agitation, or confusion,

the medication should be discontinued and seek medical advice immediately.   Click to listen highlighted text! Adverse Reactions 1.This medication may cause drowsiness, insomnia, increased weight, headache, blurred vision, dry mouth and throat, abnormal menstruation, breast engorgement and galactorrhea, syncope, orthostatic hypotension. 2.This medication may cause obesity. Risk of epilepsy is increased. 3.If you take this medication and many of these symptoms occur together such as: fever, muscle spasm, myoclonus, agitation, or confusion, the medication should be discontinued and seek medical advice immediately.  


  Drug storage

Store in a dry place away from light; at a temperature 15-30 degrees Celsius.   Click to listen highlighted text! Drug storage Store in a dry place away from light; at a temperature 15-30 degrees Celsius.


The above information is drug information used for patient self-care only.

If you have any inquiries, please ask your physicians or pharmacists.   Click to listen highlighted text! The above information is drug information used for patient self-care only. If you have any inquiries, please ask your physicians or pharmacists.


ที่มาของข้อมูล:

-นริสา ตัณฑัยย์, พาขวัญ ปุณณุปูรต, วุฒิรัต ธรรมวุฒิ, ผุสดี ปุจฉาการ, นิติ โอสิริสกุล, ชัยรัตน์ ฉายากุล, บรรณาธิการ. ข้อมูลยาประชาชน : ฉลากยาเสริม และข้อมูลความปลอดภัยในการใช้ยา. กรุงเทพฯ: โรงพิมพ์เดือนตุลา ; 2561.

-Clozapine. In: In Depth Answers [database on the Internet]. Greenwood Village (CO): IBM Corporation; 2020 [cited 2020 Dec 17]. Available from: www.micromedexsolutions.com.  


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