Drug Information
Dolutegravir (Tegrad) 50 mg
Indication
Dolutegravir is indicated in combination with other anti-retroviral medicinal products for the treatment of Human Immunodeficiency Virus (HIV) infected adults and adolescents above 12 years of age. Click to listen highlighted text! Indication Dolutegravir is indicated in combination with other anti-retroviral medicinal products for the treatment of Human Immunodeficiency Virus (HIV) infected adults and adolescents above 12 years of age.
Contraindications and precautions
1.Do not use in the patients with a history of hypersensitivity to the active substance or to any of the excipients.
2.Avoid using this medication in lactating women.
3.Dolutegravir should be used during pregnancy only if the expected benefit justifies the potential risk to the foetus.
Click to listen highlighted text! Contraindications and precautions 1.Do not use in the patients with a history of hypersensitivity to the active substance or to any of the excipients. 2.Avoid using this medication in lactating women. 3.Dolutegravir should be used during pregnancy only if the expected benefit justifies the potential risk to the foetus.
Recommendations of drug use
-If the patient misses a dose of Dolutegravir, the patient should take Dolutegravir as soon as possible, providing the next dose is not due within 4 hours.
-Do not take this medication with antacids, calcium, zinc, vitamins or supplements containing calcium or iron, should be taken 2 hours before or 6 hours after these medications. Click to listen highlighted text! Recommendations of drug use -If the patient misses a dose of Dolutegravir, the patient should take Dolutegravir as soon as possible, providing the next dose is not due within 4 hours. -Do not take this medication with antacids, calcium, zinc, vitamins or supplements containing calcium or iron, should be taken 2 hours before or 6 hours after these medications.
Adverse Reactions
1.Very common (≥10%): This medication may cause headache, nausea, diarrhea.
2.Common (≥1%): This medication may cause insomnia, abnormal dreams, depression, dizziness, vomiting, flatulence, upper abdominal pain, stomachache, abdominal discomfort, rash, pruritus, fatigue, Alanine aminotransferase (ALT) and/or Aspartate aminotransferase (AST) elevations, Creatine phosphokinase (CPK) elevations.
3.Uncommon (<1%): This medication may cause hypersensitivity reaction (such as: severe rash, or rash accompanied by raised liver enzymes), hepatitis, suicidal ideation (particularly in patients with a pre-existing history of depression or psychiatric illness.) Click to listen highlighted text! Adverse Reactions 1.Very common (≥10%): This medication may cause headache, nausea, diarrhea. 2.Common (≥1%): This medication may cause insomnia, abnormal dreams, depression, dizziness, vomiting, flatulence, upper abdominal pain, stomachache, abdominal discomfort, rash, pruritus, fatigue, Alanine aminotransferase (ALT) and/or Aspartate aminotransferase (AST) elevations, Creatine phosphokinase (CPK) elevations. 3.Uncommon (<1%): This medication may cause hypersensitivity reaction (such as: severe rash, or rash accompanied by raised liver enzymes), hepatitis, suicidal ideation (particularly in patients with a pre-existing history of depression or psychiatric illness.)
Drug storage
Store below 30 degree Celsius; in original container. Click to listen highlighted text! Drug storage Store below 30 degree Celsius; in original container.
The above information is drug information used for patient self-care only.
If you have any inquiries, please ask your physicians or pharmacists. Click to listen highlighted text! The above information is drug information used for patient self-care only. If you have any inquiries, please ask your physicians or pharmacists.
ที่มาของข้อมูล:
-เอกสารกำกับยา Dolutegravir.
-แนวทางการตรวจวินิจฉัย รักษาและป้องกันการติดเชื้อเอชไอวี ประเทศไทย ปี 2564/2565.